Ph.D. Candidacy Examination Public Presentation and Examination

Jiacheng Chuan, Ph.D. Candidate in ESC

"Bioinformatics methods for metagenomics classification; pros and cons”

Metagenomics has developed rapidly for years, from microbial diversity to functional analysis, from drug discovery to diagnostic trials. Laying the foundation for those applications, classification algorithms and methods have been iterated quickly to fulfill insatiable demands. The taxonomic resolution of metagenomics classifiers has been evolved from the genus to species level and even the strain level. In this review, it is summarized the typical metagenomic classification methods for amplicon- and shotgun-based sequencing and compared the pros and cons of matching algorithms based on k-mer, alignment, assembly, and combined methods. Also, it is discussed the current issues on metagenomic classification, including taxonomic assignment, database update, algorithm suitability, and data interpretation.

Via Google meet.  All are welcome to attend. Please contact Barry Linkletter at GSC@upei.ca for the information to connect.