Dr. David Sackett, OC, FRSC, MD, ScD, FRCP (Ottawa, London, Edinburgh), and Professor Emeritus at McMaster University is the former Director of the NHS R&D Centre for Evidence-Based Medicine at the University of Oxford, and founder of the Trout Research & Education Centre, where he reads, researches, writes and teaches about randomized clinical trials. He has written 10 books, contributed chapters to some 50 others, and has penned more than 300 articles in leading peer-reviewed journals. The 2010 Gairdner Lecture is made possible by the generous support of the PEI department of Innovation and Advanced Learning and the PEI BioAlliance. A reception will follow the lecture.